Graduate School of Informatics

This thesis examines clozapine effects on cognitive function and brain connectivity in schizophrenia with the M1 muscarinic receptor polymorphism (rs2067477). Differences in cortical activity and connectivity between genotypes were assessed using an N-back working memory task and functional near infrared spectroscopy (fNIRS). Wild-type individuals exhibited higher cortical activation during the task, but had lower functional connectivity in the frontotemporal network compared to non-wild-types. The findings suggest different compensatory mechanisms by highlighting the genetic effects of clozapine-related neural responses and provide valuable information for personalized treatment approaches in schizophrenia.

Date: 10.01.2025 / 10:00 Place: A-212

This thesis addresses the challenge of concept drift in machine learning, where evolving data patterns reduce model relevance and performance. This research proposes a dynamic system that detects and adapts to new concepts by developing tailored models for each concept. It includes leveraging ensemble strategies and mitigating class imbalances with synthetic data. By using detection techniques based on differences between datasets and performance metrics, and different prediction techniques that take account of the concept of the datasets that will be predicted this research aims to enhance model adaptability in dynamic environments, providing a comprehensive framework to tackle concept drift.

Date: 27.12.2024 / 14:00 Place: A-212

Date: 20.12.2024 / 13:00 Place: A-212

This thesis aims to understand the applicability of virtual reality or mixed reality environments to perform model-based systems engineering and develop a prototype for a framework for such uses. By conducting user tests with people from systems engineering and interactive application and game development background, identifies the primary advantages and disadvantages of using these environments compared to desktop environment. The outcomes serve as a strong baseline for possible future research and established that the virtual reality or mixed reality environments can be suitable for model-based systems engineering.

Date: 26.11.2024 Place: A-212

This thesis presents a method of comparing the cost-effectiveness of 3D mesh simplification algorithms using the McGurk effect, where visual and auditory cues are combined to create an illusion. The study involves designing a human head mesh, animating mouth movements, and recording certain syllable sounds to produce a virtual scene. Using this virtual scene and applying three different mesh simplification algorithms on the animated head, a user study was conducted to test and measure the effectiveness of each algorithm for each different syllable in medium and high difficulty levels. Results highlight the balance between computational efficiency and perceptual accuracy, providing insights for 3D modeling and virtual reality applications.

Date: 29.11.2024 / 10:00 Place: A-212

Active Directory (AD) is one of the most widely used directory services today, playing a key role in organizing and managing network resources within an organization. A robust security strategy is crucial to prevent and detect AD attacks, which can be difficult to detect due to their blend in with normal network traffic. One such attack is the Kerberoasting attack, which exploits weaknesses in the Kerberos authentication protocol. To detect these attacks, supervised machine learning algorithms are being proposed. And also publicly available dataset to measure the efficiency of these algorithms for Kerberoasting attacks was created and shared.

Date: 22.11.2024 / 14:00 Place: A-108