Perceptual sound field reconstruction (PSR) is a spatial audio recording and repro-duction method based on the application of stereophonic panning laws in microphone array design. 

Date: 08.01.2020 Place: SPARG LAB. (Modsimmer Building)

In this study, we propose to integrate large-scale gene/protein annotation data by using non-negative matrix factorization (NMF). Using NMF, the ultimate aim here is to predict the unknown binary relationships between these biological entities; and to represent these entities (i.e., proteins, functions and disease entries) as informative and non-redundant quantitative feature vectors (using the low-rank feature matrices generated by the factorization process), which can be used in diverse data mining and machine learning tasks in the future, such as the automated annotations of proteins or the construction of biological knowledge graphs.

Date: 30.01.2020 / 15:30 Place: A-212

Studies showed that single nucleotide variations that alter the protein sequence, structure and function are associated with many diseases in humans. However, the current rate of manually annotating reported nsSNPs cannot catch up with the rate of producing new sequencing data. To aid this process, automated computational approaches are being developed and applied on the unknown data. In this study, we propose a new methodology to collect and organize the information related to the effects of nsSNPs at the amino acid sequence level from various biological databases and to utilize this information in a supervised machine-learning based system to predict the function disrupting capacities of mutations with unknown consequences.

Date: 30.01.2020 / 14:00 Place: A-212

Sorafenib is one of FDA approved targeted agents in HCC treatment. PI3K/AKT pathway is altered in 50% of hepatoma, hence understanding how Sorafenib and PI3K/AKT pathway inhibitors act at signalling level is crucial for targeted therapies and to reveal their off-target effects. In this work, we use gene expression profiles of HCC cells treated with seven different drugs/inhibitors and combination. Our aim is to reveal the important targets and modulators in a drug treatment by inferring the dysregulation of Interactome. In other words, we search for the mechanism of action of drugs in a network context beyond gene list.

Date: 13.01.2020 / 14:00 Place: A-108

This thesis consists of three eye tracking applications. Main purpose of the applications is to develop a communication system for users by tracking eye movements.

Date: 14.01.2020 / 16:00 Place: A-212

This study is about using a persuasive game as a tool to raise awareness about trolling behavior. A game about online trolling behavior is designed and implemented. After exploring how the toxic behaviors that are considered as trolling in the context of online gaming are perceived, this study observes if the persuasive game has an influence in raising awareness and knowledge about these behaviors.

Date: 09.12.2019 / 10:00 Place: A-212

Features extracted from speech are widely used for problems such as biometric speaker identification, but the use of speech data raises concerns about privacy. We propose a method for speech and posture classification using only breath data. The acoustical information was extracted from breath instances using the Hilbert-Huang transform and fed into our CNN-RNN network for classification. We also created our publicly available dataset, BreathBase, which contains more than 5000 breath instances of 20 participants in 5 different postures with 4 different microphones. Using this data, 85% speaker classification and 98% posture classification accuracy is obtained.

Date: 27.11.2019 / 15.00 Place: A-212

There is a high demand for realistic computer aided imagery by many applicatiion areas such as games and movies. Due to the complicated characteristics of certain natural phenomena such as fire, smoke or mist, it is difficult to realistically mimic these effects. There are various approximation methods to visually synthesize lifelike 3D artifacts. The use of flow fields to guide the motion of particles creates a random but natural-looking effect. The aim of this study is to use flow fields to generate realistic 3D visual effects.

Date: 06.12.2019 / 13:00 Place: B-116

In this study, firstly, the effect of kinemorphs on F-formation shapes are investigated by focusing on the differences between the virtual environment and the real life settings. Secondly, the role of one-to-one F-formation shapes on joining a dyadic interaction as a third interactant is also studied.

Date: 12.09.2019 / 15:00 Place: A-212

Our project brings together the concept of sound generation from free text input. Because a good story text can describe an environment quite well, both in terms of visual and aural aspects, we decided to use this feature to create virtual soundscapes that will both be generated procedurally and have the depth, complexity and control of a story text. In this thesis we describe the mechanics of analyzing free text user input queries and a way of converting this analysis into procedural soundscape generation.

Date: 05.09.2019 / 10:00 Place: A-108